Arsenal, currently sitting second in the Premier League, welcome third-placed Newcastle United to the Emirates Stadium for what promises to be a tightly contested showdown between two top-four rivals.
Leicester City face off against Ipswich Town in a crucial relegation scrap between the Premier League’s 19th and 18th-placed sides.
Brentford welcomes Fulham on Sunday in a compelling mid-table showdown, with the hosts sitting eighth and the visitors close behind in 11th in the Premier League table.
West Ham United welcomes Nottingham Forest in a Premier League clash featuring a bottom-half battle, with the Hammers sitting 15th and Forest surprisingly up in seventh.
Everton welcomes Southampton in a poignant Premier League match, marking their farewell at Goodison Park before relocating to Bramley-Moore Dock.
Andoni Iraola's Bournemouth and Unai Emery’s Aston Villa go head-to-head at the Vitality Stadium on Saturday, with both clubs aiming to cap off the campaign by securing a spot in European competition.
Fulham host Everton this weekend as Marco Silva’s men aim to keep their late-season European hopes alive.
Already-relegated Ipswich Town are in for a tough test on Saturday as they go up against a Brentford side still in the hunt for a potential European spot to cap off their campaign.
Already-relegated Southampton face a resurgent Manchester City outfit, who are pushing to secure a second-place finish in what has been an underwhelming campaign for the former Premier League title holders.
On Saturday's Premier League fixture, Wolverhampton Wanderers welcomes Brighton & Hove Albion as 13th meets 10th in the league standings.